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MKI67 / Ki67

marker of proliferation Ki-67

Thought to be required for maintaining cell proliferation.

Gene Name:	marker of proliferation Ki-67
Synonyms:	MKI67, Antigen KI-67, Ki67, KIA
Target Sequences:	NM_002417 NP_002408.3 P46013

Publications (13)

Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft. Krishnamachary B, Glunde K, Wildes F, Mori N, Takagi T, Raman V, Bhujwalla ZM. Cancer research. 2009 69:3464-71. [PubMed:19336572] [PMC:PMC2687146]

Transforming growth factor- adaptor, 2-spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancer. Baek HJ, Pishvaian MJ, Tang Y, Kim TH, Yang S, Zouhairi ME, Mendelson J, Shetty K, Kallakury B, Berry DL, Shin KH, Mishra B, Reddy EP, Kim SS, Mishra L. Hepatology (Baltimore, Md.). 2011 53:1676-84. (IHC; Mouse) [PubMed:21520178] [PMC:PMC3162321]

AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice. Kiyota T, Ingraham KL, Swan RJ, Jacobsen MT, Andrews SJ, Ikezu T. Gene therapy. 2012 19:724-33. (ICC; Mouse) [PubMed:21918553] [PMC:PMC3241853]

Krppel-like factor 4 regulates intestinal epithelial cell morphology and polarity. Yu T, Chen X, Zhang W, Li J, Xu R, Wang TC, Ai W, Liu C. PloS one. 2012 7:e32492. [PubMed:22384261] [PMC:PMC3286469]

Endometrial sarcomas: an immunohistochemical and JAZF1 re-arrangement study in low-grade and undifferentiated tumors. Jakate K, Azimi F, Ali RH, Lee CH, Clarke BA, Rasty G, Shaw PA, Melnyk N, Huntsman DG, Laframboise S, Rouzbahman M. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2013 26:95-105. (IHC; Human) [PubMed:22918161]

The FGFR4-G388R single-nucleotide polymorphism alters pancreatic neuroendocrine tumor progression and response to mTOR inhibition therapy. Serra S, Zheng L, Hassan M, Phan AT, Woodhouse LJ, Yao JC, Ezzat S, Asa SL. Cancer research. 2012 72:5683-91. (IHC; Mouse) [PubMed:22986737]

The breast cancer susceptibility gene product fibroblast growth factor receptor 2 serves as a scaffold for regulation of NF-B signaling. Wei W, Liu W, Cassol CA, Zheng W, Asa SL, Ezzat S. Molecular and cellular biology. 2012 32:4662-73. (IHC; Mouse, Human) [PubMed:22988296] [PMC:PMC3486185]

Intra-amniotic LPS causes acute neuroinflammation in preterm rhesus macaques. Schmidt AF, Kannan PS, Chougnet CA, Danzer SC, Miller LA, Jobe AH, Kallapur SG. Journal of neuroinflammation. 2016 13:238. (IF; Rhesus monkey) [Full Text Article] [PubMed:27596440] [PMC:PMC5011884] Related Antibodies: LS-C175347.

Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores the angiogenic homeostasis and suppresses tumor progression. Antonio G Solimando, Matteo C Da Vià, Patrizia Leone, Paola Borrelli, Giorgio A Croci, Paula Tabares, Andreas Brandl, Giuseppe Di Lernia, Francesco P Bianchi, Silvio Tafuri, Torsten Steinbrunn, Alessandra Balduini, Assunta Melaccio, Simona De Summa, Antonella Argentiero, Hilka Rauert-Wunderlich, Maria A Frassanito, Paolo Ditonno, Erik Henke, Wolfram Klapper, Roberto Ria, Carolina Terragna, Leo Rasche, Andreas Rosenwald, Martin K Kortüm, Michele Cavo, Domenico Ribatti, Vito Racanelli, Hermann Ein. Haematologica. 2020 April; [Full Text Article] [PubMed:32354870] [PMC:PMC8252928] Related Antibodies: LS-C175347.

Nod-like receptors are critical for gut-brain axis signalling in mice. Matteo M Pusceddu, Mariana Barboza, Ciara E Keogh, Melinda Schneider, Patricia Stokes, Jessica A Sladek, Hyun Jung D Kim, Cristina Torres-Fuentes, Lily R Goldfild, Shane E Gillis, Ingrid Brust-Mascher, Gonzalo Rabasa, Kyle A Wong, Carlito Lebrilla, Mariana X Byndloss, Charles Maisonneuve, Andreas J Bäumler, Dana J Philpott, Richard L Ferrero, Kim E Barrett, Colin Reardon, Mélanie G Gareau. The Journal of physiology. 2019 December;597:5777-5797. [Full Text Article] [PubMed:31652348] [PMC:PMC6911019] Related Antibodies: LS-C141898.

A murine model of pediatric inflammatory bowel disease causes microbiota-gut-brain axis deficits in adulthood. Eloisa Salvo, Patricia Stokes, Ciara E Keogh, Ingrid Brust-Mascher, Carly Hennessey, Trina A Knotts, Jessica A Sladek, Kavi M Rude, Michelle Swedek, Gonzalo Rabasa, Mélanie G Gareau. American journal of physiology. Gastrointestinal and liver physiology. 2020 Sep;319:G361-G374. [Full Text Article] [PubMed:32726162] [PMC:PMC7509259] Related Antibodies: LS-C141898.

Targeting stanniocalcin-1-expressing tumor cells elicits efficient antitumor effects in a mouse model of human lung cancer. Kotaro Abe, Masahiko Kanehira , Shinya Ohkouchi, Sakiko Kumata, Yamato Suzuki, Hisashi Oishi, Masafumi Noda, Akira Sakurada, Eisaku Miyauchi, Tohru Fujiwara, Hideo Harigae, Yoshinori Okada. Cancer medicine. 2021 May;;10:3085-3100. [Full Text Article] [PubMed:33826244] [PMC:PMC8085941] Related Antibodies: LS-B6433.

Myelin as a regulator of development of the microbiota-gut-brain axis. Ciara E Keogh, Danielle H J Kim, Matteo M Pusceddu, Trina A Knotts, Gonzalo Rabasa, Jessica A Sladek, Michael T Hsieh, Mackenzie Honeycutt, Ingrid Brust-Mascher, Mariana Barboza, Mélanie G Gareau. Brain, behavior, and immunity. 2021 January;91:437-450. [Full Text Article] [PubMed:33157256] [PMC:PMC7749851] Related Antibodies: LS-C141898.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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