Mitofusin 2 / MFN2

mitofusin 2

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.

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Products

Antibodies (63)

Proteins (8)

ELISA Kits (6)

Type

Custom (2)

Over-Expression Lysate (4)

Primary (63)

Recombinant (4)

Sandwich (4)

Target

Mitofusin 2 / MFN2 (77)

Reactivity

Human (56)

Mouse (30)

Rat (38)

Bat (6)

Bovine (6)

Chicken (6)

Chimpanzee (6)

Dog (6)

Gibbon (6)

Guinea pig (6)

Hamster (3)

Horse (6)

Monkey (7)

Orangutan (6)

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Xenopus (3)

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IHC (32)

IHC-P (4)

WB (56)

ELISA (15)

ICC (10)

IF (4)

IP (3)

Peptide-ELISA (2)

RNAi (1)

Host

rabbit (50)

mouse (13)

Product Group

IHCPlus (1)

Isotype

IgG (31)

IgG2a (11)

IgG2a,k (2)

Clonality

monoclonal mc (13)

polyclonal pc (50)

Clone

4H8 (1)

6A8 (1)

S153-5 (11)

Format

96-Well Microplate (1)

96-Well Strip Plate (5)

AP Conjugated (2)

APC Conjugated (4)

Atto 390 Conjugated (2)

Atto 488 Conjugated (2)

Atto 594 Conjugated (2)

Azide-free (2)

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FITC Conjugated (7)

HRP Conjugated (5)

Magnetic beads Conjugated (1)

PE Conjugated (2)

PerCP Conjugated (2)

RPE Conjugated (2)

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Unconjugated (24)

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Epitope

aa370-600 (10)

aa447-476 (6)

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aa110-159 (4)

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Internal (2)

Cytoplasmic Domain (1)

Phe403 (1)

aa354-403 (1)

aa601-757 (1)

Publications

No (77)

Sample Type

Cell Lysates (2)

Plasma (2)

Serum (2)

Tissue Homogenates (3)

Tag

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (6)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Low Endotoxin Level

Low endotoxin level (1)

Select

Human Mitofusin 2 / MFN2 (Sandwich ELISA) ELISA Kit - LS-F31902

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mitofusin 2 / MFN2 Antibody (clone 6A8) LS-C133609

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Human Monoclonal (6A8) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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Mitofusin 2 / MFN2 Antibody LS-C336179

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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Mitofusin 2 / MFN2 Antibody (clone 4H8) LS-C133610

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Human Monoclonal (4H8) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, IHC-P, RNAi, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

Mitofusin 2 / MFN2 Antibody (aa110-159) LS-C80503

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Human Polyclonal (aa110-159) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

Mitofusin 2 / MFN2 Antibody LS-C147007

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$431

Select

Human Mitofusin 2 / MFN2 (Sandwich ELISA) ELISA Kit - LS-F65541

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Mitofusin 2 / MFN2 Antibody (APC) LS-C775121

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

APC Conjugated

Price:

100 µg/$479

Select

Mitofusin 2 / MFN2 Antibody LS-C806999

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5) LS-C209550

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

Unconjugated

Price:

100 µg/$442

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5, Biotin) LS-C229264

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (Biotin) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

Biotin Conjugated

Price:

100 µg/$475

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5, FITC) LS-C229265

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (FITC) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

FITC Conjugated

Price:

100 µg/$472

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5, APC) LS-C229263

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (APC) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

APC Conjugated

Price:

100 µg/$478

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5, AP) LS-C229262

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (AP) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

AP Conjugated

Price:

100 µg/$474

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5, PerCP) LS-C229268

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (PerCP) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

PerCP Conjugated

Price:

100 µg/$478

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5, RPE) LS-C229269

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (RPE) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

RPE Conjugated

Price:

100 µg/$477

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5, Atto 488) LS-C230123

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (Atto 488) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

Atto 488 Conjugated

Price:

100 µg/$479

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5, Atto 390) LS-C230122

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (Atto 390) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

Atto 390 Conjugated

Price:

100 µg/$479

Select

Mitofusin 2 / MFN2 Antibody (aa370-600, clone S153-5, Atto 594) LS-C230125

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (aa370-600) (Atto 594) (S153-5) Antibody

Reactivity:

Mouse, Rat

Applications:

ICC, IHC, WB

Format:

Atto 594 Conjugated

Price:

100 µg/$479

• Unconjugated
• Biotin
• FITC
• APC
• AP
• PerCP
• RPE
• More...
  • Atto 488
  • Atto 390
  • Atto 594

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • AP
  • PerCP
  • RPE
  • Atto 488
  • Atto 390
  • Atto 594

Select

Mitofusin 2 / MFN2 Antibody LS-C754630

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

Mitofusin 2 / MFN2 Antibody LS-C748646

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

IHC-plus™ Mitofusin 2 / MFN2 Antibody LS-B15154

(4.0) Rating

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

Mitofusin 2 / MFN2 Antibody (Internal) LS-C384516

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

Mitofusin 2 / MFN2 Antibody (clone S153-5) LS-C760257

Antibody:

Mitofusin 2 / MFN2 Mouse anti-Mouse Monoclonal (S153-5) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µg/$537

Select

Mitofusin 2 / MFN2 Antibody LS-C496886

Antibody:

Mitofusin 2 / MFN2 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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