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MITF

microphthalmia-associated transcription factor

Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

Gene Name: microphthalmia-associated transcription factor
Synonyms: MITF, BHLHe32, CMM8, MI, Waardenburg syndrome, type 2A, WS2, WS2A
Target Sequences: NM_000248 NP_000239.1 O75030

Publications (2)

1
Conditioned Media from Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Inhibits Melanogenesis by Promoting Proteasomal Degradation of MITF. Kim ES, Jeon HB, Lim H, Shin JH, Park SJ, Jo YK, Oh W, Yang YS, Cho DH, Kim JY. PloS one. 2015 10:e0128078. (WB; Human) [Full Text Article] [PubMed:26024475] [PMC:PMC4449211] Related Antibodies: LS-C199259.
2
Mitochondrial dynamics regulate melanogenesis through proteasomal degradation of MITF via ROS-ERK activation. Kim ES, Park SJ, Goh MJ, Na YJ, Jo DS, Jo YK, Shin JH, Choi ES, Lee HK, Kim JY, Jeon HB, Kim JC, Cho DH. Pigment cell & melanoma research. Nov;27:1051-62. [Full Text Article] [PubMed:25065405] Related Antibodies: LS-C199259.

☰ Filters
Antibodies (81)
ELISA Kits (8)
Proteins (7)
Cell-Based (1)
Cell-Based Phosphorylation (1)
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Primary (81)
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MITF (96)
Human (78)
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1607CT834.207.47 (1)
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MITF Antibody - Western blot analysis of lysates from COS7 cells, using MITF (Phospho-Ser180/73) Antibody. The lane on the right is blocked with the phospho peptide.
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MITF Rabbit anti-Human Polyclonal (pSer180/Ser73) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MITF Antibody - Immunohistochemistry analysis of paraffin-embedded human skin tissue, using MITF Antibody. The picture on the right is blocked with the synthesized peptide.
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MITF Rabbit anti-Human Polyclonal (aa151-200) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MITF Antibody - Confocal immunofluorescence of MITF Antibody with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
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MITF Rabbit anti-Human Polyclonal (aa1-28) Antibody
Human
Flo, IF, WB
Unconjugated
400 µl/$393
MITF Antibody - Immunohistochemical staining using microphthalmia antibody on formalin fixed, paraffin embedded human melanoma.
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MITF Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
GS, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$686
MITF ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
MITF Antibody - A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MITF Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$397
MITF ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MITF Antibody - IHC of MiTF on FFPE Melanoma tissue.
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MITF Mouse anti-Human Monoclonal (C5/D5) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$316
MITF Antibody - Formalin-fixed, paraffin-embedded human melanoma stained with MITF antibody (MITF/915).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MITF Mouse anti-Human Monoclonal (MITF/915) Antibody
Dog, Human
IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
MITF Antibody - Formalin-fixed, paraffin-embedded human melanoma stained with MITF antibody (MITF/915).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MITF Mouse anti-Human Monoclonal (Ready-to-Use) (MITF/915) Antibody
Dog, Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
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MITF Rabbit anti-Human Polyclonal (aa1-28) Antibody
Human
ELISA, Flo, IF, WB
Unconjugated
200 µl/$734
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MITF Rabbit anti-Human Polyclonal (aa1-28) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, WB
FITC Conjugated
200 µl/$952
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MITF Rabbit anti-Human Polyclonal (aa1-28) (PE) Antibody
Human
ELISA, Flo, ICC, IF, WB
PE Conjugated
200 µl/$952
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MITF Rabbit anti-Human Polyclonal (aa1-28) (APC) Antibody
Human
ELISA, Flo, ICC, IF, WB
APC Conjugated
200 µl/$952
MITF ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
MITF Protein - Recombinant Microphthalmia Associated Transcription Factor (MITF) by SDS-PAGE
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E. coli
His, N-Terminal
62kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
MITF Antibody - IHC testing of FFPE human melanoma with MITF antibody (clone MPAF3).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MITF Mouse anti-Human Monoclonal (MPAF3) Antibody
Human
IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
MITF Antibody - 1:100 staining rat ovarian tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MITF Rabbit anti-Human Polyclonal (pSer180,pSer73) Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MITF Antibody - MITF antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MITF Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
MITF Antibody - Formalin-fixed, paraffin-embedded human melanoma stained with anti-MITF antibody (SPM290).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MITF Mouse anti-Human Monoclonal (N-Terminus) (SPM290) Antibody
Human
IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
MITF Antibody - Formalin-fixed, paraffin-embedded human melanoma stained with anti-MITF antibody (SPM290).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MITF Mouse anti-Human Monoclonal (N-Terminus) (Azide-free, BSA-free) (SPM290) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
MITF Antibody - Formalin-fixed, paraffin-embedded human melanoma stained with MITF antibody (D5).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MITF Mouse anti-Human Monoclonal (N-Terminus) (Azide-free, BSA-free) (D5) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
MITF Antibody - Formalin-fixed, paraffin-embedded human melanoma stained with MITF antibody (D5).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MITF Mouse anti-Human Monoclonal (N-Terminus) (Ready-to-Use) (D5) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
MITF Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human skin tissue using MITF (Ab-180/73) antibody.
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MITF Rabbit anti-Human Polyclonal (p180/73) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
MITF Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MITF Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 96 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).