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Anti-MICU1 / CBARA1 Antibody (aa210-259) LS-C205435

Catalog Size Price
LS-C205435-50 50 µg (1 mg/ml) Unavailable

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14 MICU1 / CBARA1 Antibodies

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Anti-MICU1 / CBARA1 Antibody LS-C498257
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100% Guaranteed
Rabbit Polyclonal to Human MICU1 / CBARA1
Human, Monkey, Mouse, Rat, Bovine, Goat, Guinea pig, Horse, Pig, Rabbit
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human MICU1 / CBARA1
Rabbit
Human, Monkey, Mouse, Rat, Bovine, Goat, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

MICU1 / CBARA1 antibody was raised against synthetic peptide located between aa210-259 of human MICU1 (Q9BPX6, NP_001182448). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Rat, Ferret, Bovine, Goat, Elephant, Panda, Rabbit, Horse, Pig, Guinea pig, Platypus (100%).
aa210-259
Human MICU1 / CBARA1

Packaging

Lyophilized from PBS, 2% sucrose.
50 µl Distilled water
Long term: -20°C; Short term: +4°C
For research use only.

About MICU1 / CBARA1

Q9BPX6 NM_006077 NP_006068.2

MICU1 Antibody, Ara CALC Antibody, CBARA1 Antibody, CALC Antibody, EFHA3 Antibody, Mitochondrial calcium uptake 1 Antibody, Allergen Hom s 4 Antibody, Atopy related autoantigen Antibody, Atopy-related autoantigen CALC Antibody

Key regulator of mitochondrial calcium uniporter (MCU) required to increase calcium uptake by MCU when cytoplasmic calcium is high. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, respectively. MICU1 acts as a stimulator of MCU that senses calcium level via its EF-hand domains: enhances MCU opening at high Ca2+ concentration, allowing a rapid response of mitochondria to Ca2+ signals generated in the cytoplasm.

Western blot

Western blot
MICU1 / CBARA1 antibody Western Blot of MCF7. Antibody dilution: 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 10/18/2017

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