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Anti-MICA Antibody (aa23-308) LS-C149998

Catalog Size Price
LS-C149998-25 25 µg Unavailable
LS-C149998-100 100 µg Unavailable

Related Products

42 MICA Antibodies

Most Popular MICA Antibodies

Anti-MICA Antibody (aa201-250) LS-C40461
Rabbit Polyclonal (IgG) to Human MICA
Human
Western blot
Unconjugated
Western blot Image
Anti-MICA Antibody (C-Terminus) IHC-plus™ LS-B1377
Rabbit Polyclonal (IgG) to Human MICA
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-MICA Antibody (Biotin) LS-C124112
Mouse Monoclonal (IgG2a) to Human MICA
Human
IHC - Frozen, Flow Cytometry
Biotin Conjugated
Anti-MICA Antibody (aa23-308) LS-C149998
Goat Polyclonal (IgG) to Human MICA
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MICA Antibody (aa75-105, Biotin) LS-C279575
Rabbit Polyclonal (IgG) to Human MICA
Human
IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Biotin Conjugated

100% Guaranteed
Goat Polyclonal (IgG) to Human MICA
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human MICA
Goat
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 - 15 µg/ml)
  • Western blot (0.1 µg/ml)
  • ELISA (1.2 µg/ml)

Specificity and Use

MICA antibody was raised against mouse myeloma cell line NS0-derived recombinant human MICA Ala23-Gln308 Accession # NP_001 170990.
aa23-308
Detects human MICA in direct ELISAs and Western blots. In Western blots, approximately 40% cross-reactivity with recombinant human.
Western Blot, 0.1 µg/ml, Recombinant Human MICA Fc Chimera. Immunohistochemistry, 5-15 µg/ml, Blockade of Receptor-ligand Interaction, In a functional ELISA, 0.4-1.2 µg/ml of this antibody will block 50% of the binding of 50 ng/ml of biotinylated. Recombinant Human MICA Fc Chimera to immobilized Recombinant Human NKG2D Fc Chimera coated at 2 µg/ml (100 ul/well). At 5 µg/ml, this antibody will block >90% of the binding.

Packaging

Lyophilized from 0.2 um filtered solution in PBS, trehalose
Sterile PBS. Resuspend to 500 ul
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About MICA

Q29983 NM_000247 NP_000238.1

MICA Antibody, HLA class I antigen Antibody, MIC-A Antibody, PERB11.1 Antibody

MICA is the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.

Immunohistochemistry

Immunohistochemistry
MICA in Human Breast Cancer Tissue. MICA was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using Goat Anti-Human MICA Antigen Affinity-purified Polyclonal Antibody at 15 ug/ml overnight at 4 °C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

Requested From: 
Date Requested: 12/16/2017

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