MIB1

mindbomb E3 ubiquitin protein ligase 1

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis By similarity. Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation.

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Products

Antibodies (42)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (42)

Recombinant (4)

Target

MIB1 (48)

Reactivity

Human (38)

Mouse (7)

Rat (5)

Zebrafish (4)

Application

IHC (15)

IHC-P (1)

WB (30)

Flo (2)

ELISA (28)

ICC (6)

IF (3)

Peptide-ELISA (1)

Host

rabbit (38)

mouse (3)

sheep (1)

Isotype

IgG (29)

IgG1 (2)

IgG2a,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (39)

Clone

2A7B1 (1)

3E10 (1)

6A9C9 (1)

Format

APC (1)

APC Conjugated (3)

Azide-free (4)

Biotin Conjugated (5)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (3)

Unconjugated (19)

Epitope

aa769-1000 (8)

aa13-42 (7)

C-Terminus (6)

N-Terminus (1)

aa365-461 (1)

Publications

No (47)

Yes (1)

Tag

GST, N-terminus (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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MIB1 Antibody (aa13-42) LS-C99610

(4.0) Rating

(1) Publication(s)

Antibody:

MIB1 Rabbit anti-Human Polyclonal (aa13-42) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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MIB1 Antibody (clone 6A9C9) LS-C682402

Antibody:

MIB1 Mouse anti-Human Monoclonal (6A9C9) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

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MIB1 Antibody LS-C336165

Antibody:

MIB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, ICC, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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MIB1 Antibody (aa13-42, Biotin) LS-C225904

Antibody:

MIB1 Rabbit anti-Human Polyclonal (aa13-42) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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MIB1 Antibody (aa13-42, FITC) LS-C225906

Antibody:

MIB1 Rabbit anti-Human Polyclonal (aa13-42) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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MIB1 Antibody (aa13-42, Azide-free) LS-C327902

Antibody:

MIB1 Rabbit anti-Human Polyclonal (aa13-42) (Azide-free) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated, Azide-free

Price:

200 µl/$734

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MIB1 Antibody (aa13-42, APC) LS-C225903

Antibody:

MIB1 Rabbit anti-Human Polyclonal (aa13-42) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MIB1 Antibody (aa13-42, PE) LS-C225909

Antibody:

MIB1 Rabbit anti-Human Polyclonal (aa13-42) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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MIB1 Antibody (aa13-42, Azide-free, HRP) LS-C225907

Antibody:

MIB1 Rabbit anti-Human Polyclonal (aa13-42) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Biotin
• FITC
• Unconjugated, Azide-free
• APC
• PE
• HRP, Azide-free

• Biotin
• FITC
• Unconjugated, Azide-free
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

MIB1 Antibody LS-C814220

Antibody:

MIB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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MIB1 Antibody LS-C211423

Antibody:

MIB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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MIB1 Antibody (HRP) LS-C211424

Antibody:

MIB1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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MIB1 Antibody (Biotin) LS-C211426

Antibody:

MIB1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Select

MIB1 Antibody (clone 2A7B1) LS-C669529

Antibody:

MIB1 Mouse anti-Human Monoclonal (2A7B1) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

100 µl/$459

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MIB1 Antibody LS-C778994

Antibody:

MIB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MIB1 Antibody (C-Terminus, Biotin) LS-C225899

Antibody:

MIB1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MIB1 Antibody (C-Terminus, FITC) LS-C225900

Antibody:

MIB1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MIB1 Antibody (C-Terminus, Azide-free) LS-C327904

Antibody:

MIB1 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated, Azide-free

Price:

200 µl/$734

Select

MIB1 Antibody (C-Terminus, APC) LS-C225898

Antibody:

MIB1 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

Select

MIB1 Antibody (C-Terminus, Azide-free, HRP) LS-C225902

Antibody:

MIB1 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

MIB1 Antibody (C-Terminus, PE) LS-C225905

Antibody:

MIB1 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

• Biotin
• FITC
• Unconjugated, Azide-free
• APC
• HRP, Azide-free
• PE

• Biotin
• FITC
• Unconjugated, Azide-free
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

MIB1 Antibody LS-C756480

Antibody:

MIB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

MIB1 Antibody LS-C782230

Antibody:

MIB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

MIB1 Antibody LS-C807146

Antibody:

MIB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

MIB1 Antibody (aa769-1000) LS-C295376

Antibody:

MIB1 Rabbit anti-Human Polyclonal (aa769-1000) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345

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