Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat, Mouse (tested or 100% immunogen sequence identity)
Tissue culture supernatant
IHC - Frozen
Specificity and Use
Cells from R8 strain rat.
This antibody recognizes rat MHC Class 2 RT1Bu/Du and was generated in R8 rats. It crossreacts with haplotypes c, d, l, and n. Positively stains MHC class II molecules in rat strains including PVG, F334, LEW and BN. Species Crossreactivity: Mouse; recognizes mouse MHC Class 2, binding to a monomorphic epitope expressed by all mouse strains. This antibody will not react with Wistar rats as they are RT1a and this antibody is known to not react with RT1a haplotype rats.