Rat MHC Class II RT1.Bu

Mouse

Rat (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

Phycoerythrin

Ion exchange chromatography

Unmodified

Rat thymocyte membrane glycoproteins

Recognizes a polymorphic determinant of rat Ia antigen (RT1. Bu) present on Lewis, Wistar and AO strain rats, but not RN, DA or PVG/c strains. The antibody cross-reacts with mouse strains (MHC haplotypes b and s) and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region. It recognizes Ia antigens on B cell, dendritic cells and certain epithelial cells. It is particularly useful for distinguishing Ia positive cells from different rat strains, e. g. for recognizing cells of donor origin in bone marrow reconstituted radiation chimeras.

• Flow Cytometry

Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Lyophilized from PBS, pH 7.2, 0.1% Sodium Azide, 1% BSA

For research use only. Intended for use by laboratory professionals.

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