Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 7-16.17] (IgG2a) to Mouse MHC Class II I-Ap (public; Ia. m57)
Mouse MHC Class II I-Ap (public; Ia. m57)
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [7-16.17]
Protein G purified
Flow Cytometry (0.5 µg/10E6 cells)
Specificity and Use
Anti-I-Ap monoclonal antibody is a cytotoxic antibody which defines a public I-A antigen. This antibody reacts with I-A antigen from the following I-A haplotypes: I-Ap, k, q, r, s, b. Using recombinant strains, reactivity against the b haplotype has been
PBS, 0.02% sodium azide, EIA grade BSA.
Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.