Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 37.68] (IgG2a) to Sheep MHC Class II DR Monomorphic
Sheep, Human, Bovine, Goat
Sheep MHC Class II DR Monomorphic
Sheep, Human, Bovine, Goat (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [37.68]
Flow Cytometry (1:5 - 1:10)
Specificity and Use
Splenocytes from ATL mice (1).
Recognizes a monomorphic epitope on ovine MHC class II DR molecules. The distribution of ovine DR molecules on T lymphocytes has been shown to vary with immune status and age. Initially T lymphocytes lack class II molecules, then T lymphocytes progressively express DR molecules.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells in 100 ul. Method sheets are available on request.
PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.