Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 38.27] (IgG1) to Sheep MHC Class II DQ Monomorphic
Sheep, Bovine, Goat
IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Sheep MHC Class II DQ Monomorphic
Sheep, Bovine, Goat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [38.27]
IHC - Frozen
Flow Cytometry (1:1 - 1:10)
(applications tested for the base form of this product only)
Specificity and Use
Ovine efferent duct lymphocytes.
Recognizes a monomorphic epitope on ovine MHC class II DQ molecules. The distribution of ovine DQ molecules on T lymphocytes has been shown to differ with immune status and age. Expression of DQ is upregulated after recent activation.
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells in 100 ul. Method sheets are available on request.
PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.