Sheep MHC Class II DQ DR Polymorphic

Mouse

Sheep, Human, Bovine, Goat (tested or 100% immunogen sequence identity)

IgG2a Monoclonal

49.1

FITC

Affinity purified

Unmodified

Recognizes a polymorphic epitope on ovine MHC class II DQ and DR molecules. In recent work, this clone was found to recognize ovine MHC class II transfectants DQ - T28.1. DR - T8.1. DR - T31.3, but not DQ - T26.2 (Ballingall, K. et al.1995) The expression of ovine MHC class II molecules is restricted to B cells, activated T cells, monocytes, macrophages, dendritic cells and some endothelial and epithelial cells.

• IHC - Paraffin (1:50)
• Flow Cytometry (1:10)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells in 100 ul. Method sheets are available on request.

PBS, 0.09% Sodium Azide, 1% BSA

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

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