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Anti-MHC Class II Antibody (clone ER-TR3, FITC) LS-C96386

Ordering

Wt. Vol. Conc. Price
100 µg - - $515
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone ER-TR3]
Mouse
FITC Conjugated

Details

MHC Class II
Rat
Mouse (tested or 100% immunogen sequence identity)
Monoclonal [ER-TR3]
Fluorescein
Affinity purified
Unmodified

Specificity and Use

MHC Class II antibody was raised against murine thymic reticulum
MHC Class II antigens are heterodimers consisting of one a- chain(31-34kD) and one beta-chain (26-29kD). Antigen distribution Isolated cellsThe antigen is found on dendritic cells, B-cells and macrophages. The level of antigen detected by ER-TR1, ER-TR 2 and ER-TR 3 differs from strain to strain (see table below). Tissue Sections: The antigen is found on B-cells, interdigitating cells and macrophages in peripheral lymphoid organs but is absent from T-cells. It is also expressed as a fine reticular pattern on stromal thymic cells of the cortex and as a confluent pattern on stromal thymic cells of the medulla. Specificity: Mouse: cells expressing MHC class II antigens Other: negative on human, other unknown
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS pH 7.2, 10mg/ml BSA, 0.09% sodium azide
Store at 4°C.
For research use only.

About MHC Class II

MHC (major histocompatibility complex) class II molecules are a family of molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells. The antigens presented by class II peptides are derived from extracellular proteins (not cytosolic as in class I); hence, the MHC class II-dependent pathway of antigen presentation is called the endocytic or exogenous pathway.

Requested From: United States
Date Requested: 12/4/2016

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