Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone MRC OX-17] (IgG1) to Rat MHC Class I RT1.D
Rat MHC Class I RT1.D
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MRC OX-17]
Protein G purified
Flow Cytometry (0.5 µg/10E6 cells)
Specificity and Use
Rat spleen membrane glycoproteins depleted of Ia-A antigens.
Anti-rat RT1.D monoclonal antibody recognizes a monomorphic determinant on the alpha chain of the rat Ia antigen and appears to be the rat homologue of mouse Ia-E. It recognizes the rat Ia product present on B, but not T cells from lymph node or thoracic