Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone OX-27] (IgG2a) to Rat MHC Class I RT1Ac
Rat MHC Class I RT1Ac
Rat (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [OX-27]
Flow Cytometry (1:1)
Specificity and Use
PHA activated rat lymphocytes.
Recognizes a polymorphic determinant (c haplotype) of rat Class I MHC Antigen (RT-1A).
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.