Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone MRC OX-27] (IgG2a) to Rat MHC Class I RT1.Ac
Rat MHC Class I RT1.Ac
Rat (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MRC OX-27]
Protein G purified
Flow Cytometry (1 µg/10E6 cells)
Specificity and Use
Anti-rat RT1.Ac recognizes a polymorphic determinant of the MHC class I antigen in the rat. ("c" and "n" haplotypes). Tested positive with Brown Norway rats. Tested negative with Buffalo, Wistar, Fischer and ACI rats.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.