Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone MRC OX-27] (IgG2a) to Rat MHC Class I RT1.Ac
Rat MHC Class I RT1.Ac
Rat (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MRC OX-27]
Protein G purified
Flow Cytometry (1 µg/10E6 cells)
Specificity and Use
Anti-rat RT1.Ac recognizes a polymorphic determinant of the MHC class I antigen in the rat. ("c" and "n" haplotypes). Tested positive with Brown Norway rats. Tested negative with Buffalo, Wistar, Fischer and ACI rats.