Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone CVS22] (IgG2a) to Horse MHC Class I Monomorphic
IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Horse MHC Class I Monomorphic
Horse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [CVS22]
Also available conjugated with FITC.
Protein G purified
IHC - Frozen
(applications tested for the base form of this product only)
Specificity and Use
Recognizes monomorphic equine MHC Class I and was classified at the International Equine Leucocyte Antigen Workshop. MHC class I is expressed by all nucleated cells. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In horses, this complex is referred to as the equine leukocyte antigen (ELA) region.
PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
Flow cytometry of equine peripheral blood lymphocytes with Mouse anti-Equine MHC Class 1 , followed by Goat anti-Mouse IgG:FITC. This image was taken for the unconjugated form of this product. Other forms have not been tested.