Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [36-7-5]
IHC - Frozen
Specificity and Use
A. AL mouse splenocytes.
Reacts with the H-2Kk MHC class I alloantigen. Cross-reactivity with splenocytes of SJL/Hsd mice has been observed by flow cytometric analysis. Does not react with other (e. g., b, d, q) haplotypes.
Flow cytometry. Complement-dependent cytotoxicity. Immunohistochemistry (acetone-fixed, frozen sections only). Flow Cytometry: 1 ug/1E6 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.