Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

MFSD2A

major facilitator superfamily domain containing 2A

Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis By similarity. Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).

Gene Name: major facilitator superfamily domain containing 2A
Synonyms: MFSD2A, MFSD2
Target Sequences: NM_001136493 NP_001129965.1 Q5U3U7

Publications (1)

1
MFSD2A Promotes Endothelial Generation of Inflammation-Resolving Lipid Mediators and Reduces Colitis in Mice. Federica Ungaro, Carlotta Tacconi, Luca Massimino, Paola Antonia Corsetto, Carmen Correale, Philippe Fonteyne, Andrea Piontini, Valeria Garzarelli, Francesca Calcaterra, Silvia Della Bella, Antonino Spinelli, Michele Carvello, Angela Maria Rizzo, Stefania Vetrano, Luciana Petti, Gionata Fiorino, Federica Furfaro, Domenico Mavilio, Krishna Rao Maddipati, Alberto Malesci, Laurent Peyrin-Biroulet, Silvia D'Alessio, Silvio Danese. Gastroenterology. 2017 November;153:1363-1377.e6. [Full Text Article] [PubMed:28827082] Related Antibodies: LS-B5348.

☰ Filters
Antibodies (6)
Proteins (4)
ELISA Kits (2)
Over-Expression Lysate (2)
Primary (6)
Recombinant (2)
Sandwich (2)
MFSD2A (12)
Human (7)
Mouse (2)
Rat (1)
Chimpanzee (3)
Monkey (3)
Orangutan (3)
Rabbit (3)
IHC (2)
IHC-P (1)
WB (6)
ELISA (1)
IF (1)
rabbit (6)
Product Group
IHCPlus (1)
IgG (2)
polyclonal pc (6)
96-Well Strip Plate (2)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (3)
N-Terminus (4)
aa450-543 (1)
No (11)
Yes (1)
Plasma (2)
Serum (2)
GST (1)
His (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
MFSD2A Antibody - Anti-MFSD2A antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
MFSD2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
MFSD2A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MFSD2A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MFSD2A Antibody - Western blot of Human Thyroid Tumor. MFSD2A antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MFSD2A Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
MFSD2A Antibody - Western blot of Human Thyroid Tumor. MFSD2A antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MFSD2A Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Human, Monkey, Chimpanzee, Orangutan
WB
HRP Conjugated
100 µl/$469
MFSD2A Antibody - Western blot of Human Thyroid Tumor. MFSD2A antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MFSD2A Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Human, Monkey, Chimpanzee, Orangutan
WB
Biotin Conjugated
100 µl/$469
MFSD2A Antibody - Western blot of Human Thyroid Tumor. MFSD2A antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MFSD2A Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Human, Monkey, Chimpanzee, Orangutan
WB
FITC Conjugated
100 µl/$469
MFSD2A Protein - 12.5% SDS-PAGE of human MFSD2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
85 kDa
10 µg/$479; 25 µg/$670
Select
MFSD2A Rabbit anti-Human Polyclonal (aa450-543) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
MFSD2A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
58.4 kDa
100 µg/$494
MFSD2A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
58.4 kDa
20 µg/$150
Select
E. coli
77 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
8.58 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Viewing 1-12 of 12 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).