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MFGE8 /Lactadherin

milk fat globule-EGF factor 8 protein

Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization By similarity. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.

Gene Name: milk fat globule-EGF factor 8 protein
Synonyms: MFGE8, Breast epithelial antigen BA46, EDIL1, HP47, Lactadherin, Medin, MFGM, Milk fat globule-EGF factor 8, HsT19888, OAcGD3S, SPAG10, Sperm associated antigen 10, MFG-E8, SED1, Sperm surface protein hP47, BA46, HMFG
Target Sequences: NM_005928 NP_005919.2 Q08431

Publications (2)

1
Effect of innate antiviral glycoproteins in breast milk on seroconversion to rotavirus vaccine (Rotarix) in children in Lusaka, Zambia. Mwila-Kazimbaya K, Garcia MP, Bosomprah S, Laban NM, Chisenga CC, Permar SR, Simuyandi M, Munsaka S, Chilengi R. PloS one. 2017 December;12:e0189351. [Full Text Article] [PubMed:29284036] [PMC:PMC5746212]
2
Restoration of Circulating MFGE8 (Milk Fat Globule-EGF Factor 8) Attenuates Cardiac Hypertrophy Through Inhibition of Akt Pathway. Deng KQ, Li J, She ZG, Gong J, Cheng WL, Gong FH, Zhu XY, Zhang Y, Wang Z, Li H. Hypertension. 2017 October;70:770-779. [Full Text Article] [PubMed:28827473]

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Antibodies (59)
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MFGE8 /Lactadherin Antibody - Anti-MFGE8 / MFG-E8 antibody IHC of human placenta, trophoblast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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MFGE8 /Lactadherin Mouse anti-Human Monoclonal (B656M) Antibody
Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$495
MFGE8 /Lactadherin Antibody - Anti-MFGE8 / MFG-E8 antibody IHC of human lung, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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MFGE8 /Lactadherin Mouse anti-Human Monoclonal (1E7) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$440
MFGE8 /Lactadherin Antibody
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MFGE8 /Lactadherin Hamster anti-Mouse Monoclonal (18A2-G10) Antibody
Mouse
IHC, IHC-Fr, WB
Unconjugated
100 µg/$430
MFGE8 /Lactadherin Antibody
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MFGE8 /Lactadherin Hamster anti-Mouse Monoclonal (2422) Antibody
Mouse
Flo, IP
Unconjugated
100 µg/$430
MFGE8 /Lactadherin Antibody - Western blot of recombinant MFGE8 / MFG-E8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MFGE8 /Lactadherin Rabbit anti-Mouse Polyclonal (aa159-417) Antibody
Mouse
WB
Unconjugated
100 µl/$273; 200 µl/$300; 500 µl/$390; 1 ml/$435; 2 ml/$524; 5 ml/$883
MFGE8 /Lactadherin Antibody - HMFG Antibody western blot of HeLa cell line lysates (35 ug/lane). The HMFG antibody detected the HMFG protein (arrow).
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MFGE8 /Lactadherin Rabbit anti-Human Polyclonal (aa316-345) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
MFGE8 /Lactadherin Protein - Recombinant Milk Fat Globule EGF Factor 8 By SDS-PAGE
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E. coli
His
30.6 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
MFGE8 /Lactadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
MFGE8 /Lactadherin ELISA Kit
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Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Breast Milk, Cell Culture Supernatants, Plasma, Saliva, Serum, Urine
1 Plate/$795
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MFGE8 /Lactadherin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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MFGE8 /Lactadherin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
MFGE8 /Lactadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$798
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MFGE8 /Lactadherin Rabbit anti-Human Polyclonal (aa316-345) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
MFGE8 /Lactadherin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$856
MFGE8 /Lactadherin Antibody - MFGE8 / MFG-E8 antibody. IHC(P): Human Breast Cancer Tissue.
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MFGE8 /Lactadherin Rabbit anti-Human Polyclonal (aa165-180) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
MFGE8 /Lactadherin Antibody - Formalin-fixed, paraffin-embedded human breast carcinoma stained with MFGE8 antibody (MFG-06).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MFGE8 /Lactadherin Mouse anti-Human Monoclonal (MFG-06) Antibody
Dog, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
MFGE8 /Lactadherin Antibody - Western blot of MFGE8 / MFG-E8 antibody.
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MFGE8 /Lactadherin Rabbit anti-Rat Polyclonal (aa73-421) Antibody
Rat
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
1 - 600 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$870
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
MFGE8 /Lactadherin Protein - Recombinant Milk Fat Globule EGF Factor 8 By SDS-PAGE
Select
E. coli
His-GST, N-terminus
69.4 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
MFGE8 /Lactadherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$549
MFGE8 /Lactadherin Antibody - Formalin-fixed, paraffin-embedded human breast carcinoma stained with MFG-E8 antibody (SPM291).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MFGE8 /Lactadherin Mouse anti-Human Monoclonal (SPM291) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
MFGE8 /Lactadherin Antibody - Formalin-fixed, paraffin-embedded human breast carcinoma stained with MFG-E8 antibody (SPM291).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MFGE8 /Lactadherin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPM291) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
Viewing 1-25 of 91 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).