Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone HBME-1] (IgM) to Human Mesothelioma
IHC - Paraffin, IHC - Frozen
Mouse Monoclonal (IgM,k) to Human Mesothelioma
IHC - Paraffin
Human (tested or 100% immunogen sequence identity)
Tissue culture supernatant
IHC - Paraffin
Specificity and Use
Mesothelioma antibody was raised against a suspension of human mesothelioma cells from patients with malignant epithelial mesothelioma.
Ab is an anti mesothelial monoclonal antibody that recognizes an unknown antigen on microvilli of mesothelioma cells. Stains normal mesothelial cells as well as epithelial mesothelimias in a thick membrane pattern due to abundant lung microvilli on the surface of these cells. Species cross-reactivity: Human.
Immunohistology (Formalin/paraffin): (Ab 1:25-1:50 for 60 min at RT) Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive control: Mesothelioma.