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MECOM / EVI1

MDS1 and EVI1 complex locus

The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Gene Name: MDS1 and EVI1 complex locus
Synonyms: MECOM, AML1-EVI-1, EVI-1, EVI1, MDS1, MDS1 and EVI1 complex locus, MDS1-EVI1, Oncogene EVI1, AML1-EVI-1 fusion protein, Zinc finger protein Evi1, Myelodysplasia syndrome 1, PRDM3
Target Sequences: NM_004991 NP_004982.2 Q03112

☰ Filters
Antibodies (64)
Proteins (8)
ELISA Kits (1)
Cell-Based (1)
Over-Expression Lysate (4)
Primary (64)
Recombinant (4)
MECOM / EVI1 (73)
Human (64)
Mouse (22)
Rat (5)
Bat (6)
Bovine (6)
Chimpanzee (6)
Dog (7)
Gibbon (6)
Guinea pig (3)
Horse (7)
Monkey (7)
Pig (6)
Rabbit (7)
IHC (13)
IHC-P (8)
WB (57)
DB (2)
ELISA (25)
ICC (1)
IF (4)
Peptide-ELISA (4)
rabbit (51)
mouse (12)
goat (1)
Product Group
IHCPlus (3)
IgG (42)
IgG1 (7)
IgG1,k (1)
IgG2b,k (1)
monoclonal mc (11)
polyclonal pc (53)
1E7 (1)
2331C1a1 (2)
6A9 (1)
96-Well Microplate (1)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (9)
FITC Conjugated (9)
HRP Conjugated (9)
PE Conjugated (3)
Preservative Free (1)
Unconjugated (31)
N-Terminus (10)
aa359-408 (8)
aa1-30 (7)
aa81-109 (7)
aa324-373 (4)
aa964-1013 (4)
1-80 aa, N-terminal (1)
Met1 (1)
aa1-50 (1)
aa1205-1214 (1)
No (73)
Adherent Cell Cultures (1)
GST (1)
GST, N-terminus (2)
His (1)
Myc-DDK (Flag) (4)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
MECOM / EVI1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal (aa964-1013) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
MECOM / EVI1 Antibody - MECOM antibody LS-C29869 IHC of formalin-fixed, paraffin-embedded human Intestine. Positive label: Epithelial cells of intestinal villus indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MECOM / EVI1 Rabbit anti-Human Polyclonal (aa964-1013) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
MECOM / EVI1 Antibody - MECOM antibody LS-C29869 IHC of formalin-fixed, paraffin-embedded human Intestine. Positive label: Epithelial cells of intestinal villus indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MECOM / EVI1 Rabbit anti-Human Polyclonal (aa964-1013) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
MECOM / EVI1 Antibody - MECOM antibody LS-C29869 IHC of formalin-fixed, paraffin-embedded human Intestine. Positive label: Epithelial cells of intestinal villus indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal (aa964-1013) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
MECOM / EVI1 Antibody - Immunohistochemical analysis of EVI1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MECOM / EVI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
MECOM / EVI1 Antibody - Western blot analysis of extracts from A549 cells, using Myelodysplasia Syndrome 1 antibody.
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
MECOM / EVI1 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal (aa324-373) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
MECOM / EVI1 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal (aa359-408) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
MECOM / EVI1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
118.1 kDa
20 µg/$215
MECOM / EVI1 Antibody - Anti-MECOM rabbit polyclonal antibody at 1:500 dilution. Lane A: A549 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 118 kDa. Observed band size: 170 kDa. (We are unsure as to the identity of these extra bands.)
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, WB
Unconjugated, Preservative Free
100 µl/$412
MECOM / EVI1 Antibody - Western blot of PRDM3 antibody
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MECOM / EVI1 Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MECOM / EVI1 Antibody - Immunohistochemistry image at a dilution of 1:500 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
MECOM / EVI1 Antibody - Staining A549 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MECOM / EVI1 Antibody - 1:100 staining mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal (Met1) Antibody
Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
MECOM / EVI1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using MECOM Polyclonal Antibody at dilution of 1:60(×200)
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
MECOM / EVI1 Mouse anti-Human Monoclonal (N-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
MECOM / EVI1 Antibody - Detection limit for recombinant GST tagged MECOM is approximately 0.03 ng/ml as a capture antibody.
Select
MECOM / EVI1 Mouse anti-Human Monoclonal (6A9) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
MECOM / EVI1 Antibody - Detection limit for recombinant GST tagged MDS1 is approximately 3 ng/ml as a capture antibody.
Select
MECOM / EVI1 Mouse anti-Human Monoclonal (1E7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
MECOM / EVI1 Antibody - Immunohistochemistry of paraffin-embedded rat pancreas.
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal Antibody
Mouse
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
Select
MECOM / EVI1 Rabbit anti-Human Polyclonal (aa81-109) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
MECOM / EVI1 Antibody - Western blot analysis of immunized recombinant protein, using anti-EVI1 monoclonal antibody.
Select
MECOM / EVI1 Mouse anti-Human Monoclonal (2331C1a1) Antibody
Human
DB, WB
Unconjugated
100 µg/$486
Viewing 1-25 of 73 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).