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Anti-MDM4 / MDMX Antibody (clone 4B5) LS-C174380


Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular MDM4 / MDMX Antibodies

Anti-MDM4 / MDMX Antibody (clone 2C1) LS-C174500
Mouse Monoclonal [clone 2C1] (IgG1) to Human MDM4 / MDMX
IHC - Paraffin, Immunofluorescence, Western blot
Immunohistochemistry Image
Anti-MDM4 / MDMX Antibody (clone 3B9) IHC-plus™ LS-B13608
Mouse Monoclonal [clone 3B9] (IgG2b) to Human MDM4 / MDMX
IHC - Paraffin, Immunofluorescence, Western blot
Immunohistochemistry - Paraffin Image
Anti-MDM4 / MDMX Antibody (clone 4G3) IHC-plus™ LS-B13609
Mouse Monoclonal [clone 4G3] (IgG2b) to Human MDM4 / MDMX
IHC - Paraffin, Western blot
Immunohistochemistry - Paraffin Image

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Mouse Monoclonal [clone 4B5] (IgG1) to Human MDM4 / MDMX
IHC - Paraffin, Immunofluorescence, Western blot


Human MDM4 / MDMX
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [4B5]
Protein A/G purified


  • IHC - Paraffin (1:150)
  • Immunofluorescence (1:100)
  • Western blot (1:200 - 1:2000)

Specificity and Use

MDM4 / MDMX antibody was raised against full length human recombinant protein of human MDM4(NP_002384) produced in HEK293T cell.
Human MDM4 / MDMX


PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About MDM4 / MDMX

O15151 NM_002393 NP_002384.2

MDM4 Antibody, Mdm2-like p53-binding protein Antibody, MDMX Antibody, HDMX Antibody, MRP1 Antibody, p53-binding protein Mdm4 Antibody, Protein Mdm4 Antibody, Double minute 4 protein Antibody, MDM4-related protein 1 Antibody, Protein Mdmx Antibody

MDM4 / MDMX is a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.


IHC of paraffin-embedded Human prostate tissue using anti-MDM4 mouse monoclonal antibody.


Anti-MDM4 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MDM4.

Western blot

Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MDM4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MDM4.

Western blot

Western blot
Western blot of extracts (35 ug) from 9 different cell lines by using g anti-MDM4 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Requested From: United States
Date Requested: 10/22/2016

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