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Anti-MDM4 / MDMX Antibody (aa125-175) LS-C67243

Catalog Size Price
LS-C67243-100 100 µg Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human MDM4 / MDMX
Western blot, Immunoprecipitation, Flow Cytometry


Human MDM4 / MDMX
Human (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • Western blot (1:10000 - 1:25000)
  • Immunoprecipitation
  • Flow Cytometry

Specificity and Use

MDM4 / MDMX antibody was raised against a synthetic peptide which maps to a region between residues 125 and 175 of human ortholog of mouse double minute 4 using the numbering given in Swiss-Prot entry O15151 (GeneID 4194).
Specific for human HdmX/MDM4 protein. Other species not tested. Reactivity with mouse MdmX is unlikely owing to divergence of sequence between MdmX and HdmX/MDM4 at the site to which the epitope maps.
Suitable for use in Flow Cytometry, Western Blot and Immunoprecipitation. Immunoprecipitation: 2-5 ug/mg lysate. Western Blot: 1:10000-1:25000.


Tris-citrate/phosphate buffer, pH 7.5, 0.09% sodium azide.
For research use only.

About MDM4 / MDMX

O15151 NM_002393 NP_002384.2

MDM4 Antibody, Mdm2-like p53-binding protein Antibody, MDMX Antibody, HDMX Antibody, MRP1 Antibody, p53-binding protein Mdm4 Antibody, Protein Mdm4 Antibody, Double minute 4 protein Antibody, MDM4-related protein 1 Antibody, Protein Mdmx Antibody

MDM4 / MDMX is a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.

Requested From: 
Date Requested: 4/25/2018

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