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Anti-MDM2 Antibody (phospho-Ser166) LS-C25502

Ordering

Wt. Vol. Conc. Price
- 100 µl - $485
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MDM2 Antibodies

Anti-MDM2 Antibody (aa154-167, clone SMP14) IHC-plus™ LS-B163
Mouse Monoclonal [clone SMP14] (IgG1) to Human MDM2
Human, Monkey, Rat, Dog
IHC - Paraffin, IHC - Frozen, IHC - Resin, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-MDM2 Antibody (clone 1A7) IHC-plus™ LS-B5461
Mouse Monoclonal [clone 1A7] (IgG1,k) to Human MDM2
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MDM2 Antibody (Internal) LS-C209837
Rabbit Polyclonal (IgG) to Zebrafish MDM2
Zebrafish
IHC, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human MDM2
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human MDM2
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

MDM2 antibody was raised against synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser166 of human MDM2.
pSer166
Detects endogenous levels of MDM2 only when phosphorylated at serine 166.
Suitable for use in Western Blot. Western Blot: 1:1000.

Packaging

10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, BSA, 50% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About MDM2

Q00987 NM_002392 NP_002383.2

MDM2 Antibody, ACTFS Antibody, Double minute 2 protein Antibody, Hdm2 Antibody, MDM2 variant FB30 Antibody, HDMX Antibody, Oncoprotein Mdm2 Antibody, p53-binding protein Mdm2 Antibody, MDM2 variant FB28 Antibody

E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein.

Requested From: United States
Date Requested: 12/3/2016

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