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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MDC1 Antibody (aa679‑694) LS‑C19019
Antibody
MDC1 antibody LS-C19019 is an unconjugated rabbit polyclonal antibody to human MDC1. Validated for ELISA.
Catalog
Size
Price
LS-C19019-100
100 µg
Unavailable

Popular MDC1 Products

Antibody
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Human, Testis: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Detection of Human MDC1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-MDC1 used at a dilution of 1:1000 (1 Detection: DAB.
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Product Description

MDC1 antibody LS-C19019 is an unconjugated rabbit polyclonal antibody to human MDC1. Validated for ELISA.
About MDC1
Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. Q14676 D79992 BAA11487.2

MDC1 Antibody, Em:AB023051.5 Antibody, NFBD1 Antibody, KIAA0170 Antibody


Specifications

Target
Human MDC1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • ELISA
Immunogen
MDC1 antibody was raised against synthetic peptide from human MDC1.
Epitope
aa679-694
Specificity
Aa 679-694 of Human MDC1 (mediator of DNA damage checkpoint protein 1). MDC1 is hyper-phosphorylated in an ATM-dependent manner.
Usage
This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Reactivity in other immunoassays is unknown.
Presentation
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Storage
Store vial at -20°C prior to opening. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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