Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
MCOLN1 / Mucolipin 1 antibody was raised against synthetic peptide made to a C-terminal portion of the mouse protein (within residues 500-580). [Swiss-Prot# Q99J21]. Percent identity by BLAST analysis: Monkey (85%); Bovine (78%).
PBS, 30% glycerol, 0.1% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
MCOLN1 Antibody, MLIV Antibody, ML4 Antibody, Mucolipidin Antibody, Mucolipin 1 Antibody, MSTP080 Antibody, Mucolipidosis type IV protein Antibody, Mucolipin-1 Antibody, TRP-ML1 Antibody, TRPM-L1 Antibody, MG-2 Antibody, MST080 Antibody, TRPML1 Antibody
MCOLN1 / Mucolipin 1 is a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV.