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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MCOLN1 / Mucolipin 1 Antibody (aa531‑560) LS‑C164098
Mucolipin 1 antibody LS-C164098 is an unconjugated rabbit polyclonal antibody to human Mucolipin 1 (MCOLN1). Validated for IHC and WB.
Catalog
Size
Price
LS-C164098-400
400 µl
Unavailable

Popular MCOLN1 / Mucolipin 1 Products

Anti-MCOLN1 / Mucolipin 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B159 concentration 20 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Bat, Dog, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Detection of Mucolipin-1 in mouse brain lysates.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse
Applications: Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

Mucolipin 1 antibody LS-C164098 is an unconjugated rabbit polyclonal antibody to human Mucolipin 1 (MCOLN1). Validated for IHC and WB.
About MCOLN1 / Mucolipin 1
MCOLN1 / Mucolipin 1 is a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV. Q9GZU1 NM_020533 NP_065394.1

MCOLN1 Antibody, MLIV Antibody, ML4 Antibody, Mucolipidin Antibody, Mucolipin 1 Antibody, MSTP080 Antibody, Mucolipidosis type IV protein Antibody, Mucolipin-1 Antibody, TRP-ML1 Antibody, TRPM-L1 Antibody, MG-2 Antibody, MST080 Antibody, TRPML1 Antibody


Specifications

Target
Human MCOLN1 / Mucolipin 1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E2516 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C164098. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa531-560
Specificity
This MCOLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the C-terminal region of human MCOLN1.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

MCOLN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
MCOLN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

MCOLN1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MCOLN1 antibody detected the MCOLN1 protein (arrow).
MCOLN1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MCOLN1 antibody detected the MCOLN1 protein (arrow).

Immunohistochemistry

MCOLN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
MCOLN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

MCOLN1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MCOLN1 antibody detected the MCOLN1 protein (arrow).
MCOLN1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MCOLN1 antibody detected the MCOLN1 protein (arrow).

Immunohistochemistry

MCOLN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
MCOLN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

MCOLN1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MCOLN1 antibody detected the MCOLN1 protein (arrow).
MCOLN1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MCOLN1 antibody detected the MCOLN1 protein (arrow).

Immunohistochemistry

MCOLN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
MCOLN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

MCOLN1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MCOLN1 antibody detected the MCOLN1 protein (arrow).
MCOLN1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MCOLN1 antibody detected the MCOLN1 protein (arrow).


Requested From: 
Date Requested: 6/19/2018

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