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Anti-MCM5 Antibody (clone CRCT5.1) IHC-plus™ LS-B6277

Note: This antibody replaces LS-C11596

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MCM5 Antibodies

Anti-MCM5 Antibody IHC-plus™ LS-B2509
Rabbit Polyclonal (IgG) to Mouse MCM5
Mouse, Human, Monkey, Bat, Horse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-MCM5 Antibody (clone CRCT5.1) LS-C122108
Mouse Monoclonal [clone CRCT5.1] (IgG2b) to Human MCM5
Human
IHC - Paraffin, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone CRCT5.1] (IgG2b) to Human MCM5
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human MCM5
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [CRCT5.1]
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot

Specificity and Use

MCM5 antibody was raised against bacterially expressed human Mcm5.
Recognizes human Mcm-5 (minichromosome maintenance protein 5), also known as DNA replication licensing factor MCM5 or P1-CDC46. Mcm5 is a nuclear protein of ~95kD with an important role in the control of DNA replication. It has been reported that immunocytochemical assessment of Mcm5 expression may be of value in improving the accuracy of cervical smear testing for the detection of malignancy.
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About MCM5

P33992 NM_006739 NP_006730.2

MCM5 Antibody, CDC46 Antibody, CDC46 homolog Antibody, p1-CDC46 Antibody

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.

Immunohistochemistry

Immunohistochemistry
Anti-MCM5 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6277 concentration 10 ug/ml.
 

Requested From: United States
Date Requested: 12/6/2016

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