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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MCM3 Antibody (clone 3E11) LS‑C139330
MCM3 antibody LS-C139330 is an unconjugated mouse monoclonal antibody to human MCM3. Validated for ELISA and WB.
Catalog
Size
Price
LS-C139330-100
100 µg
Unavailable

Popular MCM3 Products

Hela cell nuclear extract was resolved by electrophoresis, transferred to nitrocellulose and probed with rabbit anti-MCM3 antibody. Proteins were visualized using a donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence system.
Species: Mouse, Human, Monkey, Rabbit
Applications: Western blot
Anti-MCM3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6800 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Bovine, Guinea pig
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry Image
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
IHC of paraffin-embedded Cal27 xenograft using MCM3 antibody at 1:500 dilution.
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot
MCM3 antibody. IHC(P): Rat Intestine Tissue.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Sheep, Chicken
Applications: IHC, IHC - Paraffin, ICC, Western blot

Product Description

MCM3 antibody LS-C139330 is an unconjugated mouse monoclonal antibody to human MCM3. Validated for ELISA and WB.
About MCM3
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. P25205 NM_002388 NP_002379.3

MCM3 Antibody, DNA replication factor MCM3 Antibody, HCC5 Antibody, HRlf beta subunit Antibody, p1-MCM3 Antibody, RLF subunit beta Antibody, RLFB Antibody, p102 Antibody, p1.h Antibody


Specifications

Target
Human MCM3
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [3E11]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
Immunogen
MCM3 antibody was raised against mCM3 (NP_002379, 26 a.a. ~ 113 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human MCM3
Usage
Western Blot: Tissue lysate, Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

MCM3 monoclonal antibody (M06), clone 3E11. Western blot of MCM3 expression in human spleen.
MCM3 monoclonal antibody (M06), clone 3E11. Western blot of MCM3 expression in human spleen.

Western blot

MCM3 monoclonal antibody (M06), clone 3E11. Western blot of MCM3 expression in human spleen.
MCM3 monoclonal antibody (M06), clone 3E11. Western blot of MCM3 expression in human spleen.

Western blot

MCM3 monoclonal antibody (M06), clone 3E11. Western blot of MCM3 expression in human spleen.
MCM3 monoclonal antibody (M06), clone 3E11. Western blot of MCM3 expression in human spleen.

Western blot

MCM3 monoclonal antibody (M06), clone 3E11. Western blot of MCM3 expression in human spleen.
MCM3 monoclonal antibody (M06), clone 3E11. Western blot of MCM3 expression in human spleen.


Requested From: 
Date Requested: 6/20/2018

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