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MCM3

minichromosome maintenance complex component 3

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

Gene Name: minichromosome maintenance complex component 3
Synonyms: MCM3, DNA replication factor MCM3, HCC5, HRlf beta subunit, p1-MCM3, RLF subunit beta, RLFB, p102, p1.h
Target Sequences: NM_002388 NP_002379.3 P25205

Publications (1)

1
Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation. Yim H, Erikson RL. Molecular and cellular biology. 2009 29:2609-21. [PubMed:19289504] [PMC:PMC2682042]

☰ Filters
Antibodies (36)
Proteins (6)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (36)
Recombinant (4)
Sandwich (1)
MCM3 (43)
Human (37)
Mouse (10)
Rat (4)
Bat (1)
Bovine (4)
Chicken (1)
Chimpanzee (6)
Gibbon (6)
Guinea pig (4)
Horse (4)
Monkey (9)
Orangutan (6)
Pig (1)
Rabbit (1)
Sheep (1)
IHC (21)
IHC-P (12)
WB (33)
ChrIP (1)
ELISA (15)
ICC (2)
IF (3)
IP (2)
Peptide-ELISA (2)
rabbit (31)
mouse (3)
goat (2)
Product Group
IHCPlus (2)
PathPlus Other (1)
IgG (29)
IgG1,k (1)
IgG2a,k (1)
IgG2a,l (1)
monoclonal mc (3)
polyclonal pc (33)
1593CT377.41.73 (1)
3E11 (1)
96-Well Strip Plate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (25)
aa36-64 (7)
aa500-550 (4)
aa696-745 (4)
aa726-775 (4)
aa1-295 (2)
631-680 aa, Internal (1)
aa13-27 (1)
aa42-302 (1)
aa699-808 (1)
No (43)
Cell Lysates (1)
Tissue Homogenates (1)
GST, N-terminus (1)
His-T7, N-terminus (2)
Myc-DDK (Flag) (3)
Human (4)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
MCM3 Antibody - MCM3 antibody. IHC(P): Human Lung Cancer Tissue.
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MCM3 Rabbit anti-Human Polyclonal (aa13-27) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
MCM3 Antibody - Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
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MCM3 Rabbit anti-Human Polyclonal (aa1-295) Antibody
Human
ChrIP, ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
MCM3 Antibody - Anti-MCM3 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MCM3 Rabbit anti-Human Polyclonal (aa726-775) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
MCM3 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MCM3 Rabbit anti-Human Polyclonal (aa726-775) (HRP) Antibody
Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
MCM3 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MCM3 Rabbit anti-Human Polyclonal (aa726-775) (Biotin) Antibody
Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
MCM3 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MCM3 Rabbit anti-Human Polyclonal (aa726-775) (FITC) Antibody
Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
MCM3 Antibody - Anti-MCM3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MCM3 Rabbit anti-Human Polyclonal (aa696-745) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
MCM3 Antibody - Anti-MCM3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MCM3 Rabbit anti-Human Polyclonal (aa696-745) (HRP) Antibody
Guinea pig, Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
MCM3 Antibody - Anti-MCM3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MCM3 Rabbit anti-Human Polyclonal (aa696-745) (Biotin) Antibody
Guinea pig, Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
MCM3 Antibody - Anti-MCM3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MCM3 Rabbit anti-Human Polyclonal (aa696-745) (FITC) Antibody
Guinea pig, Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
MCM3 Antibody - Immunohistochemistry of paraffin-embedded human oophoroma using MCM3 antibodyat dilution of 1:100 (40x lens).
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MCM3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Monkey
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MCM3 Antibody - IHC of paraffin-embedded Cal27 xenograft using MCM3 antibody at 1:500 dilution.
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MCM3 Rabbit anti-Human Polyclonal (aa42-302) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
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MCM3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Monkey
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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MCM3 Mouse anti-Human Monoclonal (aa699-808) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$705
MCM3 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using MCM3 Polyclonal Antibody at dilution of 1:30.
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MCM3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MCM3 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MCM3 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
60 µl/$460
MCM3 Antibody - Detection of Human MCM3 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-MCM3 used at a dilution of 1:1000 (1 Detection: DAB.
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MCM3 Rabbit anti-Human Polyclonal (aa500-550) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
MCM3 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using MCM3 Polyclonal Antibody at dilution of 1:25.
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MCM3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MCM3 Antibody - Detection of Human MCM3 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified goat anti-MCM3 used at a dilution of 1:1000 (1 Detection: DAB.
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MCM3 Goat anti-Human Polyclonal (aa500-550) Antibody
Human
IHC, WB
Unconjugated
10 µl/$295; 100 µl/$514
MCM3 Antibody - 1:100 staining mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MCM3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
MCM3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
MCM3 Antibody - Western blot of MCM3 pAb in extracts from Hela, K562 and 293T cells.
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MCM3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
MCM3 Antibody - MCM3 monoclonal antibody (M06), clone 3E11. Western blot of MCM3 expression in human spleen.
Select
MCM3 Mouse anti-Human Monoclonal (3E11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
MCM3 Rabbit anti-Human Polyclonal (aa36-64) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
MCM3 Antibody - Western blot analysis of extracts from K562 cells, using MCM3 Antibody.
Select
MCM3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25 of 43 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).