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Anti-MCM2 Antibody (clone 2546C1a) LS-C184630

Catalog	Size	Price
LS-C184630-50	50 µg (0.1 mg/ml)	Unavailable

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Anti-MCM2 Antibody (phospho-Ser41) LS-C285953

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Reactivity:	Human, Mouse, Rat, Bovine, Dog, Horse, Rabbit, Xenopus
Application:	IHC - Paraffin, Immunofluorescence
Format:	Unconjugated

Antibody:	Mouse Monoclonal [clone 2546C1a] (IgG1) to Human MCM2
Reactivity:	Human
Application:	ICC, Western blot, Dot Blot
Format:	Unconjugated

Details

Target:	Human MCM2
Host:	Mouse
Reactivity:	Human (tested or 100% immunogen sequence identity)
Clonality:	IgG1 Monoclonal [2546C1a]
Conjugations:	Unconjugated
Purification:	Protein G purified
Modifications:	Unmodified

Applications

Approved:

ICC
Western blot (0.2 - 2 µg/ml)
Dot Blot

Specificity and Use

Immunogen:	MCM2 antibody was raised against recombinant Human Minichromosome Maintenance Complex Component 2 (Mcm2).
Specificity:	Human MCM2

Packaging

Presentation:	PBS, pH 7.4, 1% BSA, 0.05% sodium azide
Storage:	Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
Restrictions:	For research use only.

About MCM2

Uniprot: P49736 NCBI: NM_004526 NP_004517.2

Synonyms: MCM2 Antibody, BM28 Antibody, Cell devision cycle-like 1 Antibody, D3S3194 Antibody, Cdc19 Antibody, Cyclin-like 1 Antibody, KIAA0030 Antibody, Nuclear protein BM28 Antibody, CDCL1 Antibody, MITOTIN Antibody

Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.

(More About MCM2)

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Western blot

Western blot of immunized recombinant protein using MCM2 antibody. Left: MCM2 staining. Right: Coomassie Blue staining of immunized recombinant protein.

Requested From:
Date Requested: 10/23/2017

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