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Anti-MCM2 Antibody (aa28-77) LS-C31454

Catalog Size Price
LS-C31454-100 100 µg (1 mg/ml) Unavailable

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100% Guaranteed
Rabbit Polyclonal (IgG) to Human MCM2
Human, Monkey, Bovine, Horse, Pig, Rabbit
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human MCM2
Rabbit
Human, Monkey, Bovine, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Mouse, Rat, Bat, Dog, Guinea pig (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Protein A purified
Unmodified

Applications

  • Western blot (1.25 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

MCM2 antibody was raised against synthetic peptide located between aa28-77 of human MCM2 (P49736, NP_004517). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Galago, Marmoset, Elephant, Bovine, Rabbit, Horse, Pig, Opossum, Turkey, Zebra finch, Platypus (100%); Mouse, Rat, Dog, Bat, Guinea pig (92%).
LS-E13139 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C31454. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa28-77
Human MCM2

Packaging

Lyophilized from PBS with 2% sucrose
100 µl After adding water, will consist of PBS buffer with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About MCM2

P49736 NM_004526 NP_004517.2

MCM2 Antibody, BM28 Antibody, Cell devision cycle-like 1 Antibody, D3S3194 Antibody, Cdc19 Antibody, Cyclin-like 1 Antibody, KIAA0030 Antibody, Nuclear protein BM28 Antibody, CDCL1 Antibody, MITOTIN Antibody

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.

Western blot

Western blot
Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 12/15/2017

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