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MCC

mutated in colorectal cancers

Candidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation.

Gene Name: mutated in colorectal cancers
Synonyms: MCC, MCC1, Protein MCC, Mutated in colorectal cancers
Target Sequences: nm_002387 NP_002378.1 P23508

☰ Filters
Antibodies (26)
Proteins (5)
Over-Expression Lysate (2)
Primary (26)
Recombinant (3)
MCC (31)
Human (26)
Mouse (10)
Rat (10)
Chimpanzee (3)
Guinea pig (3)
Horse (3)
Pig (3)
IHC (4)
IHC-P (1)
WB (20)
ELISA (14)
IF (2)
IP (1)
RNAi (1)
rabbit (25)
mouse (1)
IgG (20)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (25)
1A7 (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (10)
aa473-501 (7)
aa683-732 (4)
No (31)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
MCC Antibody - Immunohistochemistry Dilution at 1:500 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Select
MCC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
MCC Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
MCC Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
MCC Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
MCC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$351
MCC Antibody - Western Blot analysis of MCC expression in transfected 293T cell line by MCC monoclonal antibody (M01), clone 1A7.Lane 1: MCC transfected lysate(93.1 KDa).Lane 2: Non-transfected lysate.
Select
MCC Mouse anti-Human Monoclonal (1A7) Antibody
Human
ELISA, RNAi, WB
Unconjugated
100 µg/$423
MCC Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using MCC Polyclonal Antibody at dilution of 1:30.
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MCC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MCC Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using MCC Polyclonal Antibody at dilution of 1:30.
Select
MCC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
MCC Rabbit anti-Human Polyclonal (aa473-501) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
MCC Rabbit anti-Human Polyclonal (aa473-501) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
MCC Rabbit anti-Human Polyclonal (aa473-501) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
MCC Rabbit anti-Human Polyclonal (aa473-501) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
MCC Rabbit anti-Human Polyclonal (aa473-501) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
MCC Rabbit anti-Human Polyclonal (aa473-501) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
MCC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$749
Select
MCC Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Rat, Human
WB
HRP Conjugated
100 µl/$937
Select
MCC Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
WB
Biotin Conjugated
100 µl/$937
Select
MCC Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Rat, Human
WB
FITC Conjugated
100 µl/$937
Select
MCC Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Rat, Human
WB
PE Conjugated
100 µl/$937
Select
MCC Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Rat, Human
WB
APC Conjugated
100 µl/$937
MCC Antibody - MCC antibody Western Blot of MCF7.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MCC Rabbit anti-Human Polyclonal (aa683-732) Antibody
Human
WB
Unconjugated
100 µl/$424
MCC Antibody - MCC antibody Western Blot of MCF7.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MCC Rabbit anti-Human Polyclonal (aa683-732) (Biotin) Antibody
Mouse, Guinea pig, Rat, Pig, Horse, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
MCC Antibody - MCC antibody Western Blot of MCF7.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MCC Rabbit anti-Human Polyclonal (aa683-732) (FITC) Antibody
Mouse, Guinea pig, Rat, Pig, Horse, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
MCC Antibody - MCC Antibody western blot of U937 cell line lysates (35 ug/lane). The MCC antibody detected the MCC protein (arrow).
Select
MCC Rabbit anti-Human Polyclonal (aa473-501) Antibody
Human
WB
Unconjugated
400 µl/$393
MCC Antibody - Western blot analysis of extracts of various cell lines, using MCC antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
Select
MCC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 31 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).