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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MCAM / CD146 Antibody LS‑C8930
CD146 antibody LS-C8930 is an unconjugated mouse monoclonal antibody to chicken CD146 (MCAM). Validated for Flow and IP.
Antibody
Catalog
Size
Price
LS-C8930-500
500 µg
$485

Popular MCAM / CD146 Products

Antibody
Species: Rat
Applications: Western blot, Flow Cytometry, ELISA
Anti-MCAM / CD146 antibody IHC of human vessels in human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Anti-MCAM / CD146 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Angioscarcoma stained with anti-CD146
Species: Human
Applications: IHC

Product Description

CD146 antibody LS-C8930 is an unconjugated mouse monoclonal antibody to chicken CD146 (MCAM). Validated for Flow and IP.

Specifications

Target
Chicken MCAM / CD146
Synonyms
MCAM, CD146, CD146 antigen, Gicerin, Melanoma adhesion molecule, MUC18, p1h12
Host
Mouse
Reactivity
Chicken (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • Immunoprecipitation
  • Flow Cytometry
Immunogen
MCAM / CD146 antibody was raised against pooled Ed15 and Ed16 thymocytes from H. B15, H. B19 and H. B21 chicken embryos.
Specificity
Recognizes chicken MCAM, Mr 98kD (protein core ~84kD).
Usage
Immunoprecipitation. Flow Cytometry: 1 ug/1E6 cells.
Presentation
100 mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About MCAM / CD146
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. P43121 NM_006500 NP_006491.2


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Requested From: United States
Date Requested: 11/15/2018

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