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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MCAM / CD146 Antibody (Biotin) LS‑C8932
Antibody
CD146 antibody LS-C8932 is a biotin-conjugated mouse monoclonal antibody to chicken CD146 (MCAM). Validated for Flow, IHC and IP.
Catalog
Size
Price
LS-C8932-500
500 µg
Unavailable

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Product Description

CD146 antibody LS-C8932 is a biotin-conjugated mouse monoclonal antibody to chicken CD146 (MCAM). Validated for Flow, IHC and IP.
About MCAM / CD146
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. P43121 NM_006500 NP_006491.2

MCAM Antibody, CD146 Antibody, CD146 antigen Antibody, Gicerin Antibody, Melanoma adhesion molecule Antibody, MUC18 Antibody, p1h12 Antibody


Specifications

Target
Chicken MCAM / CD146
Host
Mouse
Reactivity
Chicken (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal
Conjugations
Biotin
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MCAM / CD146 antibody was raised against pooled Ed15 and Ed16 thymocytes from H. B15, H. B19 and H. B21 chicken embryos.
Specificity
Recognizes chicken MCAM, Mr 98kD (protein core ~84kD).
Usage
Suitable for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry (acetone-fixed, frozen tissue sections). Flow Cytometry: 1 ug/1E6 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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