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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MC4R / Melanocortin 4 Receptor Antibody (C‑Terminus) LS‑C8980
Melanocortin 4 Receptor antibody LS-C8980 is an unconjugated rabbit polyclonal antibody to human Melanocortin 4 Receptor (MC4R). Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C8980-100
100 µl
$725

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Product Description

Melanocortin 4 Receptor antibody LS-C8980 is an unconjugated rabbit polyclonal antibody to human Melanocortin 4 Receptor (MC4R). Validated for ELISA and WB.
About MC4R / Melanocortin 4 Receptor
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). P32245 NM_005912 NP_005903.2

MC4R Antibody, Melanocortin receptor 4 Antibody, MC4-R Antibody, MC4 Antibody, MC4 receptor Antibody, Melanocortin 4 receptor Antibody


Specifications

Target
Human MC4R / Melanocortin 4 Receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:100000)
Immunogen
14 aa peptide mapping near the C-terminal 4th cytoplasmic domain of human MC4-R. This peptide sequence is 100% identical in monkey, pig, and bovine, 84% with mouse, and 69% homologous with rat MC4-R. No significant sequence homology of MCR42 is seen with other melanocortin receptors.
Epitope
C-Terminus
Specificity
Recognizes human MC4-R.
Usage
Suitable for use in ELISA, Western Blot. Western Blot: 1:1000-1:5000. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well.
Presentation
PBS, pH 7.2, 0.05% Sodium Azide, 40% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/20/2018

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