Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
MC2R / ACTHR / ACTH Receptor antibody was raised against synthetic peptide ENINNTARNNSDC from the N-terminus of human MC2R (NP_000520.1). Percent identity by BLAST analysis: Human, Gorilla (100%); Gibbon, Marmoset, Sheep, Elephant, Panda, Bovine, Dog, Horse (92%); Monkey, Rat (85%).
LS-E26587 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55095. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.