Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Synthetic peptide ENINNTARNNSDC from the N-terminus of human MC2R (NP_000520.1). Percent identity by BLAST analysis: Human, Gorilla (100%); Gibbon, Marmoset, Sheep, Elephant, Panda, Bovine, Dog, Horse (92%); Monkey, Rat (85%).
LS-E26587 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55095. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.