MBNL2

muscleblind-like splicing regulator 2

Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. Seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm at adhesion plaques. May play a role in myotonic dystrophy pathophysiology (DM).

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Products

Antibodies (23)

Proteins (7)

Type

Over-Expression Lysate (4)

Primary (23)

Recombinant (3)

Target

MBNL2 (30)

Reactivity

Human (22)

Mouse (7)

Rat (7)

Bat (6)

Bovine (6)

Chicken (3)

Chimpanzee (6)

Dog (6)

Gibbon (3)

Guinea pig (6)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (6)

Rabbit (6)

Xenopus (6)

Zebrafish (3)

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Application

IHC (7)

IHC-P (1)

WB (16)

Flo (7)

ELISA (12)

ICC (1)

IF (1)

Host

rabbit (17)

mouse (6)

Isotype

IgG (12)

IgG1,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (17)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (7)

Epitope

aa261-290 (7)

aa46-95 (4)

aa51-100 (4)

aa1-80 (1)

Publications

No (30)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

MBNL2 Antibody (aa46-95) LS-C82665

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa46-95) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MBNL2 Antibody (aa46-95, HRP) LS-C454844

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa46-95) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Bat, Gibbon, Orangutan, Human, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MBNL2 Antibody (aa46-95, Biotin) LS-C454841

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa46-95) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Bat, Gibbon, Orangutan, Human, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

MBNL2 Antibody (aa46-95, FITC) LS-C454843

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa46-95) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Bat, Gibbon, Orangutan, Human, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

MBNL2 Antibody (aa261-290) LS-C164061

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa261-290) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MBNL2 Antibody (aa261-290) LS-C322890

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa261-290) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MBNL2 Antibody (aa261-290, Biotin) LS-C237454

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa261-290) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MBNL2 Antibody (aa261-290, FITC) LS-C237456

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa261-290) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MBNL2 Antibody (aa261-290, Azide-free, HRP) LS-C248775

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa261-290) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

MBNL2 Antibody (aa261-290, APC) LS-C237453

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa261-290) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MBNL2 Antibody (aa261-290, PE) LS-C237458

Antibody:

MBNL2 Rabbit anti-Human Polyclonal (aa261-290) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

MBNL2 Antibody LS-C816667

Antibody:

MBNL2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

Select

MBNL2 Antibody (aa1-80) LS-C308908

Antibody:

MBNL2 Mouse anti-Human Monoclonal (aa1-80) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$705

Select

MBNL2 Antibody (HRP) LS-C543102

Antibody:

MBNL2 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

100 µl/$904

Select

MBNL2 Antibody (Biotin) LS-C522969

Antibody:

MBNL2 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

MBNL2 Antibody (FITC) LS-C533013

Antibody:

MBNL2 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

100 µl/$904

Select

MBNL2 Antibody (APC) LS-C514754

Antibody:

MBNL2 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

APC Conjugated

Price:

100 µl/$904

Select

MBNL2 Antibody (PE) LS-C651214

Antibody:

MBNL2 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

MBNL2 Antibody LS-C747906

Antibody:

MBNL2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

MBNL2 Antibody (aa51-100) LS-C205713

Antibody:

MBNL2 Rabbit anti-Rat Polyclonal (aa51-100) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MBNL2 Antibody (aa51-100, HRP) LS-C441344

Antibody:

MBNL2 Rabbit anti-Rat Polyclonal (aa51-100) (HRP) Antibody

Reactivity:

Xenopus, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MBNL2 Antibody (aa51-100, Biotin) LS-C441342

Antibody:

MBNL2 Rabbit anti-Rat Polyclonal (aa51-100) (Biotin) Antibody

Reactivity:

Xenopus, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

MBNL2 Antibody (aa51-100, FITC) LS-C441343

Antibody:

MBNL2 Rabbit anti-Rat Polyclonal (aa51-100) (FITC) Antibody

Reactivity:

Xenopus, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Human MBNL2 Protein (Recombinant GST) (Full Length) - LS-G31983

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

66.9 kDa

Price:

2 µg/$439

Select

Human MBNL2 Protein (Recombinant GST, N-terminus) (aa1-80) - LS-G61394

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Viewing 1-25 of 30 product results

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