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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MBNL1 / MBNL Antibody (aa255‑284) LS‑C157881
MBNL antibody LS-C157881 is an unconjugated rabbit polyclonal antibody to human MBNL (MBNL1). Validated for WB.
Catalog
Size
Price
LS-C157881-400
400 µl
Unavailable

Popular MBNL1 / MBNL Products

MBNL1 antibody LS-C30383 was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Rat, Bat, Dog, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey
Applications: Western blot
Antibody (1 ug/ml) staining of HeLa lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
Species: Human, Monkey, Mouse, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-MBNL1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4372 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Immunohistochemistry of paraffin-embedded rat heart.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot

Product Description

MBNL antibody LS-C157881 is an unconjugated rabbit polyclonal antibody to human MBNL (MBNL1). Validated for WB.
About MBNL1 / MBNL
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Q9NR56 NM_021038 NP_066368.2

MBNL1 Antibody, EXP35 Antibody, EXP40 Antibody, KIAA0428 Antibody, Muscleblind (Drosophila)-like Antibody, Muscleblind-like protein 1 Antibody, MBNL Antibody, EXP Antibody, EXP42 Antibody, Muscleblind-like (Drosophila) Antibody


Specifications

Target
Human MBNL1 / MBNL
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Epitope
aa255-284
Specificity
This MBNL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-284 amino acids from the C-terminal region of human MBNL1.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

MBNL1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MBNL1 antibody detected the MBNL1 protein (arrow).
MBNL1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MBNL1 antibody detected the MBNL1 protein (arrow).

Western blot

MBNL1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MBNL1 antibody detected the MBNL1 protein (arrow).
MBNL1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MBNL1 antibody detected the MBNL1 protein (arrow).

Western blot

MBNL1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MBNL1 antibody detected the MBNL1 protein (arrow).
MBNL1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MBNL1 antibody detected the MBNL1 protein (arrow).

Western blot

MBNL1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MBNL1 antibody detected the MBNL1 protein (arrow).
MBNL1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The MBNL1 antibody detected the MBNL1 protein (arrow).


Requested From: 
Date Requested: 6/18/2018

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