Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human MBL2 / Mannose Binding Protein
Mouse Monoclonal (IgG1,k) to Human MBL2 / Mannose Binding Protein
Western blot, ELISA
Human MBL2 / Mannose Binding Protein
Human (tested or 100% immunogen sequence identity)
Protein A/G purified
Specificity and Use
Human MBL (2).
Specific for MBL from human serum or plasma. Epitope specificity differs from those of clones 6F140 and 6F142. Reacts with human MBL both in its polymeric confirmation and as a single subunit of molecular mass 26kD. Can be applied for quantitative measurement of MBL in plasma or serum.
Suitable for use in ELISA, Western Blot. ELISA: 1:10000.
PBS, pH 7.2, 15 mM sodium azide.
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.