Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
MATN4 / Matrilin 4 is a member of von Willebrand factor A domain-containing protein family. The proteins of this family are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This family member is thought to be play a role in reorganizing and regenerating the corneal matrix in granular and lattice type I dystrophies. It may also be involved in wound healing in the dentin-pulp complex.
Immunofluorescence of MATN4 in mouse brain tissue with MATN4 antibody at 20 ug/ml.
Western blot of MATN4 in rat brain tissue lysate with MATN4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. Below: Immunohistochemistry of MATN4 in mouse brain tissue with MATN4 antibody at 2.5 ug/ml.