Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
MAS1 Antibody, Mas proto-oncogene Antibody, Proto-oncogene Mas Antibody, MAS Antibody, MAS1 oncogene Antibody
Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
Immunohistochemistry: MAS1 Antibody - Analysis of MAS1 in mouse kidney using DAB with hematoxylin counterstain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry/Immunofluorescence: MAS1 Antibody - MAS1 antibody was tested at 1:25 in HepG2 cells with FITC (green). Nuclei were counterstained with Dapi (blue). This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: MAS1 Antibody - Analysis of MAS1 in: 1. Ntera 2, 2. A431, 3. HepG2, 4. MCF7, 5. 3T3 and 6. Cos7. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Requested From: United States
Date Requested: 1/16/2017