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MARCKS

myristoylated alanine-rich protein kinase C substrate

MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Gene Name: myristoylated alanine-rich protein kinase C substrate
Family/Subfamily: MARCKS , Not assigned-Other
Synonyms: MARCKS, 80K-L, 80K-L protein, MACS, MRACKS, Phosphomyristin, PKCSL, PRKCSL
Target Sequences: NM_002356 NP_002347.5 P29966

Publications (1)

1
PhosphoMARCKS drives motility of mouse melanoma cells. Chen X, Rotenberg SA. Cellular signalling. 2010 22:1097-103. (WB) [PubMed:20211725] [PMC:PMC2860666]

☰ Filters
Antibodies (55)
ELISA Kits (9)
Proteins (3)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Custom (4)
Primary (55)
Recombinant (3)
Sandwich (3)
MARCKS (67)
Human (57)
Mouse (34)
Rat (34)
Bovine (10)
Chicken (9)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Monkey (3)
Rabbit (3)
Xenopus (4)
Zebrafish (10)
IHC (15)
IHC-P (5)
WB (51)
ELISA (19)
ICC (3)
IF (12)
IP (2)
Peptide-ELISA (6)
rabbit (52)
mouse (2)
chicken (1)
Product Group
IHCPlus (2)
IgG (31)
IgG1 (1)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (53)
2C2 (1)
96-Well Microplate (2)
96-Well Strip Plate (7)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (44)
aa241-271 (7)
pSer158 (6)
aa226-275 (4)
aa256-305 (4)
pSer163 (4)
100-180 aa (3)
Internal (2)
pSer162 (2)
Arg157 (1)
C-Terminus (1)
Lys152 (1)
Ser152/Ser156 (1)
aa126-175 (1)
aa136-185 (1)
p158 (1)
p162 (1)
pSer152/Ser156 (1)
No (67)
Adherent Cell Cultures (2)
Cell Lysates (2)
Plasma (1)
Serum (1)
Tissue Homogenates (2)
GST, N-terminus (1)
His, N-Terminal (1)
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Human (3)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
MARCKS Antibody - Anti-MARCKS antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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MARCKS Mouse anti-Human Monoclonal (2C2) Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$485
MARCKS Antibody - Western blot analysis of MARCKS expression in HeLa (A); RAW264.7 (B) whole cell lysates.
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MARCKS Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Zebrafish, Bovine, Mouse, Rat, Human
IP, WB
Unconjugated
100 µl/$299
MARCKS Antibody - Anti-MARCKS antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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MARCKS Rabbit anti-Human Polyclonal (aa136-185) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
MARCKS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
Select
MARCKS Mouse anti-Human Monoclonal (C-Terminus) Antibody
Bovine, Human
ELISA, IP, WB
Unconjugated
200 µl/$884
MARCKS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$893
MARCKS Antibody - Immunofluorescent analysis of MARCKS staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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MARCKS Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Zebrafish, Bovine, Mouse, Rat, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
MARCKS Antibody - Western blot analysis of MARCKS (pS163) expression in MCF7 PMA-treated (A); SP2/0 PMA-treated (B); PC12 PMA-treated (C) whole cell lysates.
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MARCKS Rabbit anti-Human Polyclonal (pSer163) Antibody
Chicken, Zebrafish, Bovine, Mouse, Rat, Human
WB
Unconjugated
100 µl/$315
MARCKS Protein - Recombinant Myristoylated Alanine Rich Protein Kinase C Substrate (MARCKS) by SDS-PAGE
Select
E. coli
His, N-Terminal
32.7kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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MARCKS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
MARCKS Antibody - View of mixed neuron/glial cultures stained with our MARCKS antibody (red) and antibody to MAP2 made in chicken. Note that the MARCKS antibody stains vesicular structures both in the glial cells and in the dendrites of the neurons, which are strongly stained with the MAP2 antibody.
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MARCKS Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$376
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MARCKS Rabbit anti-Human Polyclonal (100-180 aa) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
MARCKS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
Select
MARCKS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
Select
MARCKS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
MARCKS Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using MARCKS (Ab-158) antibody.
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MARCKS Rabbit anti-Human Polyclonal (p158) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
MARCKS Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using MARCKS (Ab-162) antibody.
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MARCKS Rabbit anti-Human Polyclonal (p162) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
MARCKS Antibody - Immunolabeling of HeLa cells showing specific labeling of the MARCKs protein (anti-MARCKS antibody, red, 1:5000) and ß-tubulin protein (green). Anti-MARCKS binds MARCKs protein expressed in the plasma membrane and cytoplasm. The blue is Hoechst staining the nuclear DNA.
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MARCKS Chicken anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
100 µl/$469
MARCKS Antibody - Immunofluorescence analysis of A549 cells, using MARCKS Antibody. The picture on the right is blocked with the synthesized peptide.
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MARCKS Rabbit anti-Human Polyclonal (aa126-175) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MARCKS Antibody - IHCanalysis of MARCKS (R157) pAb in paraffin-embedded human brain tissue.
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MARCKS Rabbit anti-Human Polyclonal (Arg157) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
MARCKS Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MARCKS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
MARCKS Rabbit anti-Human Polyclonal (100-180 aa) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MARCKS Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using MARCKS (Phospho-Ser163) Antibody. The picture on the right is blocked with the phospho peptide.
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MARCKS Rabbit anti-Human Polyclonal (pSer163) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
MARCKS Antibody - Western blot of MARCKS (K152) pAb in extracts from PC12 cells.
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MARCKS Rabbit anti-Human Polyclonal (Lys152) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
MARCKS Rabbit anti-Human Polyclonal (pSer163) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$328; 100 µl/$419
Viewing 1-25 of 67 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).