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Anti-MAPT / Tau Antibody (phospho-Ser404) LS-C191332

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Rabbit Polyclonal (IgG) to Human MAPT / Tau
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human MAPT / Tau
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Affinity purified

Applications

Western blot (1:500 - 1:1000)

Specificity and Use

MAPT / Tau antibody was raised against synthetic phosphopeptide corresponding to human Tau around the phosphorylation site of serine 404 (D-T-SP-P-R).
pSer404
Human Tau (Ser404). Species Crossreactivity: mouse and rat.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months.
For research use only.

About MAPT / Tau

NM_016835

MAPT Antibody, FTDP-17 Antibody, MSTD Antibody, Neurofibrillary tangle protein Antibody, PHF-tau Antibody, MTBT2 Antibody, PPND Antibody, DDPAC Antibody, MAPTL Antibody, MTBT1 Antibody, Paired helical filament-tau Antibody, TAU Antibody

Tau promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.

Requested From: United States
Date Requested: 6/1/2015

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