Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1A1] (IgG1) to Human MAPT / Tau
Human, Monkey, Mouse, Rat, Bovine, Dog, Goat, Pig
IHC, Western blot
Human MAPT / Tau
Human, Monkey, Mouse, Rat, Bovine, Dog, Goat, Pig (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [1A1]
Protein A purified
IHC (2 µg/ml)
Western blot (15 µg/ml)
Specificity and Use
MAPT / Tau antibody was raised against a synthetic peptide corresponding to the E2 Junction part of human tau (KSTPTAEAEEAGIG). Percent identity by BLAST analysis: Human, Monkey, Mouse, Rat, Goat, Bovine, Dog, Pig (100%).
Human MAPT / Tau
Lyophilized from PBS, 1% BSA, 0.05% sodium azide
1 ml Distilled water
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Tau promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.