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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAPKAPK2 / MAPKAP Kinase 2 Antibody (phospho‑Thr334) LS‑C124052
Antibody
MAPKAP Kinase 2 antibody LS-C124052 is an unconjugated rabbit polyclonal antibody to MAPKAP Kinase 2 (MAPKAPK2) from human, mouse, rat and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C124052-50
50 µg (1 mg/ml)
Unavailable

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Product Description

MAPKAP Kinase 2 antibody LS-C124052 is an unconjugated rabbit polyclonal antibody to MAPKAP Kinase 2 (MAPKAPK2) from human, mouse, rat and other species. Validated for IHC and WB.
About MAPKAPK2 / MAPKAP Kinase 2
Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue. P49137 NM_004759 NP_004750.1

MAPKAPK2 Antibody, MK-2 Antibody, MAP KAP Kinase 2 Antibody, MAPKAP kinase 2 Antibody, MK2 Antibody, MAPKAP-K2 Antibody, MAPKAPK-2 Antibody


Specifications

Target
Human MAPKAPK2 / MAPKAP Kinase 2
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Chicken, Zebrafish (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:50 - 1:100)
  • Western blot (1:500 - 1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic phosphopeptide corresponding to human MAPKAPK2 around the phosphorylation site of threonine 334 (P-Q-TP-P-L).
Epitope
pThr334
Specificity
Recognizes human MAPKAP Kinase 2 when phosphorylated at Thr334. Species cross-reactivity: mouse, rat.
Usage
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:500-1:1000. Immunohistochemistry: 1:50-1:100.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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