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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAPK8IP1 / JIP1 Antibody (N‑Terminus) LS‑C16105 Best Seller
JIP1 antibody LS-C16105 is an unconjugated rabbit polyclonal antibody to JIP1 (MAPK8IP1) from human and mouse. Validated for IP and WB.
Antibody
Catalog
Size
Price
LS-C16105-100
100 µg (0.25 mg/ml)
$605

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Product Description

JIP1 antibody LS-C16105 is an unconjugated rabbit polyclonal antibody to JIP1 (MAPK8IP1) from human and mouse. Validated for IP and WB.
About MAPK8IP1 / JIP1
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Q9UQF2 NM_005456 NP_005447.1

MAPK8IP1 Antibody, JIP1 Antibody, JNK-interacting protein 1 Antibody, IB-1 Antibody, IB1 Antibody, Islet-brain 1 Antibody, JIP-1 Antibody, PRKM8 interacting protein Antibody, PRKM8IP Antibody


Specifications

Target
Human MAPK8IP1 / JIP1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 3 µg/ml)
  • Immunoprecipitation (5 - 10 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
MAPK8IP1 / JIP1 antibody was raised against synthetic peptide derived from the N-terminal region of the human JIP1 protein.
Epitope
N-Terminus
Specificity
Reacts with human and mouse JIP1. Reactivity has been confirmed with mouse brain homogenates and human embryonic kidney HEK293 cell lysates transfected with full-length JIP1. This antibody identifies an ~100-110kD isoform of JIP1 on Western blots.
Usage
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1-3 ug/ml. Immunoprecipitation: 5-10 ug/ml.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/19/2018

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