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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAPK8 / JNK1 Antibody (phospho‑Thr183/Tyr185) LS‑C16110
JNK1 antibody LS-C16110 is an unconjugated rabbit polyclonal antibody to human JNK1 (MAPK8). Validated for WB.
Antibody
Catalog
Size
Price
LS-C16110-10
10 blot
$605

Popular MAPK8 / JNK1 Products

Anti-MAPK8 / JNK1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3403 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish, Drosophila
Applications: Western blot, ELISA
Anti-MAPK8 / JNK1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6390 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
NIH/3T3 cell lysate was probed with anti-JNK at 1:200.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish, Drosophila
Applications: Western blot, ELISA
Anti-MAPK8 / JNK1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6391 concentration 2.5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA

Product Description

JNK1 antibody LS-C16110 is an unconjugated rabbit polyclonal antibody to human JNK1 (MAPK8). Validated for WB.

Specifications

Target
Human MAPK8 / JNK1
Synonyms
MAPK8, JNK, JNK1, JNK1A2, JNK-46, MAP kinase 8, PRKM8, SAPK1, SAPK1c, MAPK 8, C-Jun N-terminal kinase 1, JNK21B1/2, JUN N-terminal kinase
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
MAPK8 / JNK1 antibody was raised against synthetic phosphopeptide derived from the region of human JNK1&2 that contains threonine 183 and tyrosine 185. This region is conserved among many species including mouse, rat, chick, nematode, and fruit fly, and in JNK3.
Epitope
pThr183/Tyr185
Specificity
Human, mouse, and rat JNK1&2. Other species of JNK1&2 have not been tested, and JNK3 (found primarily only in neuronal cell lines) has not been detected.
Usage
Western blotting and immunostaining applications. Positive control: HEK 293 cells +/- UV irradiation treatment and PC12 cells +/- Sorbitol.
Presentation
1 mg/ml BSA (IgG, Protease free), PBS (without Mg2+, Ca2+), pH 7.2, 0.1% Sodium Azide, 50% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About MAPK8 / JNK1
Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. P45983 NM_139049 NP_620637.1


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Requested From: United States
Date Requested: 10/22/2018

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