Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 3C9] (IgG2a,k) to Human MAPK3 / ERK1
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Human MAPK3 / ERK1
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [3C9]
Protein A purified
IHC - Paraffin (10 µg/ml)
Immunofluorescence (25 µg/ml)
Western blot (1:500 - 1:1000)
Specificity and Use
MAPK3 / ERK1 antibody was raised against mAPK3 (AAH13992, 279 a.a. ~ 379 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot using transfected cell lysates, cell line lysates and the recombinant protein used as the immunogen.
PBS, pH 7.2
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF.